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Another limita-tion of brain reserve theory is that it does not explain thecounterintuitive finding that, once Alzheimer’s is diag-nosed, higher IQ and more education are associated withfaster deterioration and more rapid death (Stern et al.,1994; Stern et al., 1995; Teri et al., 1995; Stern et al., 1999;Scarmeas et al., 2006; Hall et al., 2007; Helzner et al., 2007).By contrast, cognitive reserve refers to the ability tomake flexible and efficient use of available brain reservewhen performing tasks (Stern, 2002). This triple formula has been considered and recently pro-moted as the most adequate way to start solving the long-lasting problems of the RDcommunity